Artemisia Annua Artemisia Carvifolia Seeds Qing Hao
Artemisia annua (Artemisia Carvifolia) 青蒿
Artemisia annua, also known as Artemisia carvifolia, sweet wormwood, sweet annie, sweet sagewort, annual or annual mugwort wormwood, is a common type of wormwood native to temperate Asia, but naturalized in many countries including scattered parts of North America.
It has fern-like leaves, bright yellow flowers, and a camphor-like scent. Its height averages about 2 m, and the plant has a single stem, alternating branches, leaves and alternating Which range from 2.5-5 cm in length. It is cross-pollinated by wind or insects. It is a plant with diploid chromosome number 2n = 18.
In traditional Chinese medicine, A. annual is traditionally used to treat fever.
In 1971, scientists Demonstrated the plant extracts had antimalarial activity in primate models, and in 1972, the active ingredient, artemisinin (formerly Referred to as arteannuin), was isolated and its chemical structure described. Artemisinin may be extracted using a low boiling point solvent, such as diethylether, and is found in the glandular trichomes of the leaves, stems, and inflorescences, and it is concentrated in the upper portions of plant Within new growth. The first isolation of artemisinin from the herb occurred from a military project known as Project 523, Following The study of traditional medicine pharmacopoeias performed by Tu Youyou and other researchers Within the project.
Research to develop antimalarial drugs led to the discovery of artemisinin, a compound Which is extracted from Artemisia annua, in the 1970s by Chinese scientist Tu Youyou, For which she shared the 2015 Nobel Prize in Physiology or Medicine. While most TCM herbs are boiled at high temperatures That can damage the active ingredient in Artemisia annua, one traditional source says That this herb is to be steeped in cold water; knowing this, scientists found a better extract That was Obtained by using a low-temperature ether-based extraction method, and by adding detoxification and purification processes, they could create a drug with sufficient active ingredient to be effective.
Artemisinin is a sesquiterpene lactone with an endoperoxide bridge and Has Been produced semisynthetically as an antimalarial drug. The efficacy of tea made from A. yearly in the treatment of malaria is contentious. According to some authors, artemesinin is not soluble in water and the Concentrations In These infusions are Considered insufficient to treat malaria. In 2004, the Ethiopian Ministry of Health changed Ethiopia's first-line anti-malarial drug from sulfadoxine / pyrimethamine (Fansidar), which has an average 36% treatment failure rate, to artemether / lumefantrine (Coartem), a drug therapy containing artemesinin Which is 100% effective When used correctly, despite a worldwide shortage at the time of the derivative needed from A. year. A 2012 review Said That artemisinin-based remedies are the most effective drugs for the treatment of malaria. A 2013 review suggested That Although artesunate may not cause hepatotoxicity, haematotoxicity, or hyperlipidemia, it Should be used cautiously during pregnancy two to a potential risk of embryotoxicity at a high dose.
Despite Global Efforts in Combating malaria, it remains a large burden for the population, Particularly in tropical and subtropical regions. Although WHO recommends artemisinin-based remedies for treating uncomplicated malaria, artemisinin resistance can no longer be ignored. The causes That affected the emergence of artemisinin resistance includes, for example, the use of artemisinin-based remedies. Encouraging herbal alternatives are in the pipeline, but the only indelible solution for the eradication of malaria would be for the creation of an effective vaccination. Emergence of artemisinin resistance Has Been Identified in the border of Thailand and Cambodia. Likely it will spread to other endemic areas across the world in the impending future. As of 2013, It Seems That the pathogenic agent of malaria is slowly becoming resistant to artemisinin-based drugs.
Animal experiments Showed That artesunate, a synthetic derivative of artemisinin, has anti-allergic properties, by effecting mast cell degranulation. This makes artesunate a candidate for treatment of allergic asthma. In animal studies further Top Strengthens Metabolomics this hope.
The mechanism of action of artemisinin Theproposed Involves cleavage of endoperoxide bridges by iron, producing free radicals (hypervalent iron-oxo species, epoxides, aldehydes, and dicarbonyl compounds) Which damage biological macromolecules causing oxidative stress in the cells of the parasite. Malaria is Caused by apicomplexans, primarily Plasmodium falciparum, Which largely reside in red blood cells and itself contains iron-rich heme-groups (in the form of hemozoin).
Cancer drug research
Synthetic derivatives of artemisinin are being investigated for Their potential use as anticancer drugs.
We Guarantee Your Purchases Will Be Delivered On-time and As Described
Quanzhou City, Fujian Province, China
This Store Has Been Open Since Apr 12, 2013
1. When you’ve found a product you like, make sure you check product specifications such as size and color. You can also find more detailed information, such as sizing tables, if you scroll down the product detail page.
2. Some sellers also offer coupons. You can find them in their store and the product detail pages.
3. When you’re ready to place your order, you can click “Buy Now” and continue to the checkout, or you can add the product to your cart first and continue shopping.
4. If you want buy all the items in your cart, simply click “Buy All” to place your order
Note: once the order has been paid, you are unable to change the shipping address. However, you can contact the seller to send him/her any updates.
Share this Product
- choosing a selection results in a full page refresh